• Cryo-electron microscopy (cryo-EM), a powerful technique for visualizing 3D shapes of biological molecules, typically requires highly concentrated samples, posing a challenge for studying rare molecules.
• Researchers have developed Magnetic Isolation and Concentration cryo-electron microscopy (MagIC), a novel method that overcomes this limitation by enabling the study of samples 100 times more dilute than previously possible, as detailed in a study published in eLife.