IVF and Preimplantation Genetic Testing: Reducing the Risk of Genetic Disorders in India
• Genetic disorders are prevalent in India due to its large population, high birth rate, and common practice of consanguineous marriages.
• Common genetic disorders in India include thalassemia, sickle cell anemia, cystic fibrosis, Duchenne muscular dystrophy, fragile X syndrome, and Down syndrome.
• IVF combined with Preimplantation Genetic Testing (PGT) allows screening of embryos for specific genetic abnormalities and selection of unaffected embryos for transfer.
• PGT includes techniques like PGT-A for aneuploidy screening, PGT-M for monogenic diseases, and PGT-SR for structural rearrangements.
• IVF with PGT empowers individuals and couples with genetic disorders to make informed choices and reduce the risk of passing on genetic disorders to their children.